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The addition of the GIP hormone appears to create a synergistic effect that supports deeper fat loss and better blood sugar regulation

The authors attribute this shift to an imbalance between endothelium-derived relaxing factors (EDRFs)nitric oxide, prostacyclin, endothelium-derived hyperpolarizing factors, and natriuretic peptidesand endothelium-derived contracting factors (EDCFs), including endothelin-1, thromboxane A2, reactive oxygen species, and Rho-kinase signaling

They are also believed to have a role in improving the energy level and immune system function, although strong clinical evidence supporting these effects remains limited

Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial